Exosome treatment uses microscopic biological messengers — vesicles that carry growth factors, proteins, and regenerative signals — to instruct your skin cells to repair, rebuild, and produce more collagen. Unlike topical skincare that works on the surface, exosome therapy works at the cellular level. At New Age Spa, we deliver exosome compounds through Dermapen DP4 microneedling micro-channels for maximum dermal penetration and absorption. We offer two formulations: salmon DNA (PDRN) exosomes and plant-based vegan PDRN.

In many cases, yes — and increasingly so. PRP (platelet-rich plasma) uses growth factors from your own blood, which varies in potency depending on each client's platelet count and requires a blood draw before every session. Exosome formulations — whether salmon DNA or plant-based — are purified for consistent, targeted regenerative signaling. No blood draw, no session-to-session variability, faster results, and more predictable outcomes. PRP depends on your body's variable biology. Exosomes guide your body with precise regenerative signals. That's why more clinics in Montreal are moving toward exosome protocols.

Salmon DNA (PDRN — polydeoxyribonucleotide) is the regenerative ingredient used in one type of exosome-based treatment. PDRN activates the A2A adenosine receptor, triggering a cellular cascade of tissue repair, collagen synthesis, and inflammation suppression. The exosomes are the delivery vehicle — microscopic vesicles that carry PDRN and other regenerative signals to the cells. Together, they form the salmon DNA exosome protocol. Our plant-based vegan PDRN alternative uses different source compounds (plant stem cells, bioengineered peptides) to deliver similar regenerative signals without animal-derived ingredients. See the full salmon DNA exosomes page for deeper detail.

Yes — we offer plant-based vegan PDRN as a fully vegan alternative to salmon DNA exosomes. This formulation uses plant stem cells, bioengineered nucleotides, and growth factor-mimicking peptides to deliver cellular regenerative signals without any animal-derived ingredients. It is also the recommended option for clients with known fish or marine allergens for whom salmon DNA PDRN is contraindicated. Both options are available at all four of our Greater Montreal locations.

Typically 3–4 sessions spaced 4–6 weeks apart for optimal results — the same protocol structure for both salmon DNA and plant-based vegan PDRN. This is a compounding-effect treatment: each session builds on the cellular repair initiated in the previous one. For anti-aging and general rejuvenation, 2–3 sessions delivers visible improvement. For moderate acne scarring or significant texture concerns, 4 sessions is the standard protocol. Your esthetician designs your personalized session plan at your initial assessment. Maintenance every 3–6 months sustains long-term results.

Minimal — and less than standard microneedling alone for both protocols. Mild redness and skin sensitivity for 24–48 hours is typical, resolving faster because PDRN (both formulations) actively accelerates cellular repair from within rather than waiting for the standard healing timeline. Avoid heat, heavy exercise, and active skincare products for 48 hours. Most clients return to regular activities the same day or the day after. SPF every morning without exception is the most important aftercare step.

Mild discomfort at most. Medical-grade numbing cream is applied before the microneedling phase and takes full effect within 20–30 minutes — built into your appointment time, not an extra wait. The exosome serum application itself is notably soothing: both salmon DNA and plant-based formulations have anti-inflammatory properties. Most clients describe the combined session as significantly more comfortable than they expected, and noticeably more comfortable than standard microneedling without exosomes.

Initial glow and improved texture are visible within 3–7 days of the first session. Firmer skin, reduced fine lines, and progressive scar improvement develop within 2–4 weeks as collagen remodels and cellular repair continues beneath the surface. Full results from a 3–4 session protocol are typically visible 6–8 weeks after the final treatment. Collagen production and tissue remodelling continue for 4–6 weeks after each session — assess results at the 4-week mark, not immediately post-treatment.

Yes — treatments can be customized and alternated within a multi-session plan. Some clients use salmon DNA for their primary regeneration protocol and switch to plant-based vegan PDRN for maintenance sessions, or vice versa. Both options can also be strategically paired with chemical peels or laser skin rejuvenation in a multi-modality protocol. Your esthetician designs the most effective combination at your initial assessment.

At New Age Spa — with four locations across Greater Montreal: Downtown Montreal, Laval, Saint-Léonard, and West Island. Both salmon DNA exosome treatment and plant-based vegan PDRN are available at all four locations, performed by certified estheticians trained at our CIDESCO and CAMACS-recognized academy. Book your assessment at booking.mangomint.com or call 1-888-808-0955.